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Waterfall plots illustrate the percentage change from baseline to the 12-month follow-up for each participant across six clinical domains: MDS-UPDRS Part I, Part II, Part III (Off-state), Part III (On-state), Part IV, and Total MDS-UPDRS score

Abstract Skin homeostasis depends on interactions between epithelial cells and the microbiome mediated by molecular and biochemical factors

10.1038/s41574-019-0273-8 Nat

This subpopulation of LARS B cells shows a preference for Leu metabolism, which can be induced by a Leu diet to promote mitochondrial NAD + production and oxidative metabolism and recruit NAD + -dependent protein deacetylase SIRTUIN-1 (SIRT1) to participate in the regulation of LARS B cells

Currently, the small application range of targeted therapy drugs and recurrence and drug resistance after radiotherapy and ablation treatment lead to the unoptimistic overall treatment effect of advanced liver cancer, and the 5-year survival rate is low (Schlachterman et al., 2015)

GFR, glomerular filtration rate