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Animal studies showed accelerated dermal healing in normal rats, steroid-treated rats, diabetic mice, and aged mice, all populations with compromised healing capacity similar to chronic eczema patients

HPLC and MS/MS validation performed per batch

Using an elegant approach based on biological nanopore sensors incorporated into artificial lipid membranes, the authors monitored the escape of various substrates from the pore

doi: 10.1083/jcb.114.5.1089

Bringhen S, Pour L, Vorobyev V, et al

The practical cutoff for effective passive sublingual absorption sits around 10 kDa (10,000 Daltons) for unenhanced formulations
