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Whereas, a large number of ROS including superoxide (O 2 ), hydroxyl radical (OH ), perhydroxyl radical (HO 2 ), and other types such as hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HOCl), and lipid peroxides (ROOH) [9], is generated as by-products of cellular aerobic metabolism upon different physiological and pathological changes, once exceeding the capacity of the cellular reductase mechanisms, which can result in direct or indirect functional damage to different molecules such as proteins, nucleic acids, and lipids, and eventually lead to cell death [10, 11]

gossypii strain W122032, modified by the mutated DNA polymerase , losing its DNA repair function and introducing errors in the lagging strand, and increasing the riboflavin yield up to 13.7 g/L for 9 days of cultivation in optimized medium containing waste edible oils

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Kim D.H

Glutathione is crucial for enzyme and hormone production and supports immune function

It is a core cofactor for multiple metalloenzymes, including cytochrome c oxidase, superoxide dismutase, and ceruloplasmin (CP), and is deeply involved in basic life processes such as cellular energy metabolism, antioxidant defense, and neurotransmitter synthesis [2,3,4,5]