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doi: 10.1016/j.neubiorev.2021.08.029

The anti-inflammatory and anabolic attributes of ozone therapy have garnered notable attention

Clinical Trials Friedreich's Ataxia (FA) and Spinocerebellar Ataxia FA COMS A Study of the Clinical Progression of FA in concert with the Friedreich's Ataxia Research Alliance (FARA) Network FFA Biomarker Study A Study of New Tools to Measure and Track the Clinical progression of FA (including new gait and balance measures) Intravenous Immunoglobulin Therapy in FA and SCA3 Study of the Natural History of SCA types 1,2,3 & 6 Parkinson's Disease (PD) and Essential Tremor (ET) Vesicare for Urinary Incontinence in PD Cognitive Aging in PD Patients Constipation and PD A Therapeutic Study for Progressive Supranuclear Palsy (PSP) Treatment of Dyskinesias in PD TETRAS Primidone for the treatment of ET

427,428,429 The compound NLY01 is particularly effective at attenuating the activity of proinflammatory microglia and preventing the transformation of astrocytes to a reactive phenotype

"Changes in muscle mass and phenotype and the expression of autocrine and systemic growth factors by muscle in response to stretch and overload." Journal of Anatomy, 194(3), 323-334

Furthermore, transcranial magnetic stimulation (TMS) or direct current stimulation (tDCS) enhances recovery even when treatment is instituted months after the stroke