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11 The antecedent Selyes organoprotective issue, the damage consequent to acute nonspecific nocuous agents that produce the organism severely damaged in rat experiments, 22 since the very beginning, clearly indicated what should be the essential proof of concept and interposed agent activity supposed to be involved in the counteractive coping response organization

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A connection between diabetic corneal ulcers and diabetic foot ulcers (DFUs) has been proposed: they share many aspects of impaired wound healing resulting from neurovascular, sensory, and immunologic compromise [7]

10.1038/s41598-023-34916-z 117 RobertsT