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Within endosomes, Fe 3+ is reduced back to Fe 2+ primarily by six-transmembrane epithelial antigen of prostate 3 (STEAP3) in vivo (Ohgami et al., 2006

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The FADS1 gene is located very near to the FADS2 gene on chromosome 11q12.2 and is composed of 13 exons that encode a protein of 501 amino acids

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