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Long-term follow up has shown that many affected individuals who live as male are participating in long-term, heterosexual relationships (37)

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Designed as a three-arm randomised, double-blind, placebo-controlled intervention trial, the ErgMS study will supplement participants with placebo, 5 or 30 mg/d ergothioneine for 12 weeks, taking measurements of metabolic syndrome risk factors, serum markers of oxidative stress (lipid peroxidation), inflammation, blood platelet function and liver function at baseline, and after 6 weeks and 12 weeks of supplementation (Reference Tian, Cioccoloni and Sier97)

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