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The TDLN is also a practical and clinically relevant site for biomarker discovery and therapeutic innovation as a target of drug delivery and immunomodulation

A subclinical chronic inflammation sustained by inflammatory mediators and immune cells is described in AL [24]

10.1016/j.mbs.2015.06.004 25 BiancuzziH.Dal MasF.BresciaV.CampostriniS.CascellaM.CuomoA.et al (2023)
Collectively, these alterations limit the generation of high-quality antibodies, increase susceptibility to infections, and lead to suboptimal vaccine responses

A., El Benna J

Pharmacological properties of polyphenols: Bioavailability, mechanisms of action and biological effects in in vitro studies, animal models and humans
