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Ensuring adequate protein intake, maintaining hydration, and preserving sleep quality help manage fatigue

For instance, as outlined by a national coalition of recovery and harm reduction organizations, government agencies should allocate opioid abatement funds to proven public health solutions (e.g., overdose prevention centers), housing and wraparound support services (e.g., supportive housing programs), addressing collateral consequences of Drug War policies (e.g., second-chance employment programs), and supporting community-based organizations rather than further criminalizing substance use (A Roadmap for Opioid Settlement Funds: Supporting Communities & Ending the Overdose Crisis, n.d.)

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10.1016/j.nlm.2018.04.006 Neurobiol

Together, they add up to a profound metabolic effect

The GLP-1 receptor activation happens throughout the central nervous system, including areas involved in pain perception and blood vessel regulation