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An alternate pathway for cocaine-induced BBB permeability alteration involves platelet-derived growth factor (PDGF) intermediates (Yao et al., 2011)

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doi: 10.1016/s0928-4257(99)00119-9

Mitragynine, speciogynine, paynantheine, and 7-hydroxymitragynine possess the 3 S configuration, whereas speciociliatine, mitraciliatine, and isopaynantheine possess the 3 R configuration

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Biophys J 119(2):274286 Tuner S, Gurbanov R, Sheraj I, Solel E, Esenturk O, Sreeparna B (2018) Low dose dimethyl sulfoxide driven gross molecular changes have the potential to interfere with various cellular processes