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Bibcode:2011Natur.469..236R

Likewise, Guo et al

The most recent data from 2025 continues to solidify oxidative stress as the shared mechanistic basis for post-viral syndromes

People at Risk The risk of adverse effects is especially high in people with [70+]: Digestive conditions (Crohns disease, ulcerative colitis, diverticulitis) A history of bowel surgery Severe hemorrhoids Kidney, heart, and liver disease Allergy to coffee The FDA only approves colon cleansing to prepare for medical procedures and has issued several letters warning about unapproved uses

Poor attribution skills should also make us skeptical