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There are eight types of GPX family in mammals (GPX1, GPX2, GPX3, GPX4, GPX5, GPX6, GPX7, GPX8), of which GPX1-4 and GPX6 of mammals are considered to be selenoproteins containing selenium, which have antioxidant functions, and GPX6 is only expressed in the human body ( In mammals, GPX works with superoxide dismutase and catalase to form an enzymatic antioxidant system that reduces reactive oxygen species (ROS) and limits their toxicity

Ascorbate peroxidase, glutathione peroxidase, and glutathione S-transferase all detoxify ROS or other dangerous chemicals using ascorbate or glutathione as co-substrates

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The inhibitory effects of RYGB surgery on high glucose-induced damage can be significantly blocked after administration of NADPH (36)

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In a PD yeast model, MG inhibited the development of -synuclein aggregates