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Omavaloxolone engages the cells endogenous antioxidant response, and while it can attenuate the progression of Friedreichs ataxia, it is not curative

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In contrast, the cell membrane in the forskolin (FSK) group remained intact, and the cellular nucleus showed no visible changes

MPs might also act to sequester anticancer drugs by expressing the drug efflux transporter P-gp on their surfaces, as an active mechanism, and through the diffusion of chemotherapeutic drugs, such as DOX, anthracyclines, and daunorubicin across the MP membrane, as a passive mechanism (120, 373)