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Rather, the goal is to fundamentally change the joint's biology from a pro-inflammatory, degenerative state to an anti-inflammatory, pro-reparative one

Activation of distinct mitogen-activated protein kinases pathways by copper and cadmium

Additionally, advances in nanotechnology have facilitated precise therapy by enabling targeted delivery of ferroptosis inducers or immunomodulators, transforming cold tumors into hot tumors and further boosting ICI efficacy

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

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