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Constituents such as flavonoids, terpenoids, stilbenes, and polyphenolic glycosides exert pleiotropic and often synergistic effects, including reduction of ROS, modulation of signaling pathways involved in mitochondrial dynamics, enhancement of autophagic flux through AMPK/mTOR and SIRT1 signaling, promotion of mitochondrial biogenesis through NRF1/TFAM activation, and stabilization of calcium homeostasis

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This improvement in single-cell detection was likely the result of the INS and GCG probes included in our DART-Seq beads

As an additional control, we analyzed a possible negative impact of ENDOs on cell viability

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Longitudinal associations between sex hormone-binding globulin and insulin resistance