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Our findings indicated that the ferroptosis-associated genes, which are essentially ferroptosis-resistant genes, were significantly downregulated in the Cd-treated group
Formazan crystals were solubilized in 100 L of DMSO by incubating in shaking condition at room temperature for 5 min
Based on the MichaelisMentens equation (KD is inversely proportional to affinity), quercetin binds with ACE 2 with KD value of 16 M (Fig
Management includes addressing underlying causes, lifestyle changes, and counseling
This adjusted value considers the complexity of the model and penalizes the inclusion of unnecessary variables
Nevertheless, the present study still has some limitations, as the current study has not yet externally validated our proposed risk stratification model, its clinical application still needs to be validated in external cohorts, including retrospective cohorts from other centers and future prospective multicenter cohorts
