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The prevailing theory posits that CSD triggers the release of pronociceptive mediators, leading to the dilation of meningeal arteries and activation of perivascular primary afferents, thereby causing headache [4, 5]
T., Rosetti, M
Subsequently, added 60 L of 50% acetonitrile, vortexed with shaking at 1700 rpm for 10 minutes at 8 C, centrifuged at 15,000 g for 20 minutes at 4 C, and aspirated the supernatant and stored at 80 C until analysis
PMC 3474083
Papadimitriou MC, Pazaiti A, Iliakopoulos K, Markouli M, Michalaki V, Papadimitriou CA
