nad+ or glutathione Interplay between NADH oxidation by complex I, redox state and sirtuin-3, and its role in the development of insulin resistance Redox potentials of NAD(P), glutathione,

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These actions are mediated through enhanced mitochondrial biogenesis and ATP production, inhibition of inflammatory signaling, and preservation of nigrostriatal dopaminergic neurons, collectively leading to improved motor and non-motor functional outcomes (Zhu et al., 2017