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2020 Dec 10

[21] demonstrated that pulsatile, but not continuous, GH administration to humans increased the rate of lipolysis, but this study did not address the issue of potential roles of GH peak frequency or of the baseline component of GH secretion

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These studies suggest that EDCs exposure affects the expression of GnRH and kisspeptin, influences the pulsatile launch of GnRH, and interferes with the regulation of gonadotropin production from the pituitary axis (63)