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doi: 10.1093/hmg/ddaa169 57 NewberryFHsiehSYWilemanTCardingSR

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The dose of colistin was chosen based on a preliminary experiment to determine the dose sufficient to lead to histological damage in all treated mice

Most of the cellular energy production comes from mitochondria whose main function is the production of adenosine triphosphate (ATP), which is needed to drive cellular processes (Figure 1)