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Given that DSF and copper supplements are already under clinical evaluation for cancer therapy, we expect that our findings provide valuable insights that help facilitate the clinical translation of DSF repurposing in cancer treatment

These findings position EV-ANHs as highly promising therapeutic candidates

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Ramsey KM, Mills KF, Satoh A, Imai S

A sample size of 14 will be required to detect this change with a power of 80% and a Type 1 error of 0.05

Science 383 , 413421 (2024)

It is important to emphasize that activation of the JAKSTAT3 pathway and the upregulation of GFAP should not be interpreted as substate-specific markers of astrocyte reactivity 139