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The mRNA levels of the DNA methyltransferases 1, 3a, 3b, Tet2, and Tet3, were significantly upregulated in the liver of HFD-fed mice, whereas Tet1 was downregulated considerably (Fig

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Peak plasma concentration occurs 90120 minutes post-injection, with NNMT inhibition persisting for 812 hours based on enzyme half-life kinetics

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