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In summary, the inflammatory microenvironment in IDD is extremely complex, with different cytokines and proteases regulating the survival, proliferation, migration, and differentiation fate of MSCs and disc progenitor cells in a concentration- and cell-dependent manner

doi: 10.1186/s12958-018-0391-5 90 DabeeSPassmoreJSHeffronRJaspanHB

Numerous preclinical studies have also suggested that tocotrienols might be beneficial in the prevention of chronic diseases (12)

Despite the unclear pathophysiological mechanism of the disorder, numerous studies attempted to investigate the underlying cause and mechanisms implicated in this disease, such as genetic predisposition

The unique nanocage structure combined with intrinsic tumor-targeting properties positions ferritin-based formulations as promising next-generation nanomedicines for pancreatic cancer therapy