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Evidence for lysosomal accumulation via endocytosis and consequent pH-driven nanoparticle degradation is the likely mechanism of the Au(I) cargo (Figure 26)

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2 Oxidative stress and periodontitis 2.1 Basic concepts of oxidative stress Oxidative stress refers to an imbalance between the production of reactive oxygen types (involving superoxide anions, hydrogen peroxide, etc.) and other oxidants in the cellular and extracellular environment, capable of damaging cell structures and functions ( Under normal conditions, the body regulates and neutralizes these parlous oxidants by antioxidant systems (including superoxide dismutase, glutathione peroxidase, etc.), remaining redox balance within cells (Menzel et al., 2021)

It is essential, however, for breastfeeding mothers to consult healthcare providers before introducing any new supplement into their routine

In general, it is estimated that a minimum dose of 300 mg per day is required, and that the maximum dose may reach 600 mg for the most serious conditions

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