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Description
Autophagy may precede cellular senescence of bile ductular cells in ductular reaction in primary biliary cirrhosis
These stressors can damage cellular components, trigger ROS production, and induce ferroptosis by overwhelming antioxidant defenses mediated by GPX4, as well as disrupting the cysteine-glutathione axis via System Xc- (145)
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Method: Sprague Dawley rats weighing 200-250 grams were used for the study
279 (3), E622E629
