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Intriguingly, CD8 + T cells exhibit an adaptive response by upregulating an alternative glutamine transporter, SLC6A14, thereby sustaining both glutamine uptake and immune effector function within V9302-treated tumors [134]

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[DOI] [PubMed] [Google Scholar] 668

This pathological state is like a double-edged sword: on the one hand, it may increase the passive penetration of polyphenols through the damaged mucosa, enhancing its local exposure