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These effects are mediated through downstream activation of transcription factors such as c-Fos, c-Jun, and EGR-1, which regulate genes involved in cell cycle progression, extracellular matrix remodeling, and angiogenic signaling [26]

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Regardless of mechanism, clinical observations support a nausea-reducing effect in a subset of users

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IM injections go into muscle, most often the outer thigh (vastus lateralis) or deltoid

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*High Dose Concentration IVs require blood test prior to receiving treatment, and prescription for nutrients used

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Biochemistry 57:57755779

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DIM is an essential part of BHRT "pellet" therapy

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