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First, empty capsid clearance was investigated from different cell culture harvests through optimization of GSH chromatography parameters, and if insufficient resolution is observed, the subsequent polishing chromatography steps are evaluated

In vitro knockdown NRF2 in dentate gyrus-derived NSCs have been shown to decrease their proliferation and survival, whereas NRF2 / mice showed reduced minichromosomal maintenance complex component 2 (MCM2)-positive proliferative cells and fewer Sox2- and doublecortin (Dcx)-positive NSCs (Ray et al., 2018)

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34 , 11041120.e1108 (2022)

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