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L-Carnitine (2 g/day) significantly reduced Lp(a) levels (-7.7% versus baseline and -11.7% vs placebo treat- ment), the reduction being more dramatic in the subjects with the more marked elevations. In a significant number of subjects, the reduction of Lp(a) resulted in a return of this major cardiovascular risk parameter to the normal range.4

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10.1093/ajcn/nqaa430 Summary Keywords TMAO, L-carnitine, atherosclerosis, endoplasmic reticulum stress, vascular calcification Citation Wang B, Qiu J, Lian J, Yang X and Zhou J (2021) Gut Metabolite Trimethylamine-N-Oxide in Atherosclerosis: From Mechanism to Therapy

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