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MCT1 inhibitor AZD3965 increases mitochondrial metabolism, facilitating combination therapy and noninvasive magnetic resonance spectroscopy

Myeloid cells also express triggering receptor 1 (TREM-1), which reprograms macrophage metabolism, enhances glycolytic activity, activates the NLRP3 inflammasome, and triggers an inflammatory response in ALI (Zhong, 2023)

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GABAergic neuron-specific loss of Ube3a causes angelman syndrome-like EEG abnormalities and enhances seizure susceptibility

doi: 10.1016/j.molpha.2025.100027 7 ChenL.RenS