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Under various physiological and pharmacological conditions agonist binding likely occurs to only a subset of subunits within these tetrameric receptors, motivating an analysis of the functional and conformational effects of partial versus complete ligand occupancy
Haku et al., 2018)
Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome
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& Guan, J.-L
Thus, binding of glutamate is known to increase the distance between the -carbons of Proline 632 pairs at the base of the D2 lobe of the GluA2 LBD (Fig
