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Therefore, more generic multi-step approaches can be useful to break down a complex task into more manageable steps

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A.GrigolettoJ.PoliM.ArosioP.ArkadirD.SharonR

NMDARs are widespread in the CNS and are essential mediators of synaptic transmission and plasticity

For instance, in a dopaminergic PC12 cell line, deficiencies in GSH synthesis that led to an overall decrease in cellular GSH resulted in complex I inhibition, increased indices of oxidative stress, and deficits in mitochondrial respiration, as seen in cases of Parkinsonism [15]

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