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A subsequent study that followed 43 patients for up to four years found those with mild dementia or moderate-early dementia who took lipoic acid (600 mg/day), in addition to acetylcholinesterase inhibitors, experienced slower cognitive decline compared to the typical cognitive decline of Alzheimers patients as reported in the literature (102)
Its basic structure and function, includes: SDH is involved in the both the ETC and Krebs cycle (Kc)

It turned out that glutamine deprivation suppressed cell proliferation and induced apoptosis in all cell lines tested [18]

Aleksandra Zurowska, EMJ Reference Wei Q, Zhao, J
This allows for released GSH to be broken down and its constituent amino acids taken up by cells and reincorporated into GSH (so called -glutamyl cycle, see below)
They also accumulate more cortical and basal ganglia atrophy than age-matched controls at longitudinal follow-up 7,119,121
