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Since neurotransmitters also influence mast cells, one should ensure an adequate supply of proteins and amino acids such as L-phenylalanine

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and increased absolute and relative bioavailability, which may be the result of reducing first-pass metabolism in the intestine and liver

Cancer Drug Resist 7, 50

& James, R

Given that TGR5 is found in sensory neurons and immune cells, the dramatic decrease in -muricholic acid suggests that altered activity of specific bile acids may contribute to pain in FM (96)
