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10.3389/fimmu.2021.779453 Front Immunol

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is supported by a British Heart Foundation Intermediate Clinical Research Fellowship (FS/18/23/33512)

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Excessively consuming such diets not only directly affects energy metabolism in liver, but also increases the concentration of TMAO in plasma, which promotes the development of MAFLD by affecting bile acid metabolism, unfolded protein response, and oxidative stress