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Autoantibodies in ME/CFS Another manifestation of the ME/CFS-associated immune dysregulation is the presence of autoantibodies directed against cholinergic and 2 adrenergic receptors (2AdRs) documented by numerous studies (Loebel et al., 2016

Moreover, the carbonyl and phenolic hydroxyl groups inherent to quinones serve as efficient coordination sites for metal ions, enabling construction of diverse metal-quinone supramolecular architectures [53]