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Vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), epidermal growth factor (EGF), and platelet-derived growth factor (PDGF), along with their receptors, are key proangiogenic factors

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B12 is critical for red blood cell formation, nerve function, and DNA synthesis

Since I use a tiny tuberculin needle, most patients have no problem with the injection and dont need any extra lidocaine skin wheal or freezing spray