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10.1155/2012/697237 213 WangY.HuangY.LamK

Cyanocobalamin is the most widely used form of vitamin B 12, and has hematopoietic activity apparently identical to that of the antianemia factor in purified liver extract

Free radicals are molecules that have an unpaired electron, making them unstable and reactive

This produces mutagenic and carcinogenic byproducts, including 8-hydroxy-2-deoxyguanosine (8-OHdG), 4-hydroxy-nonenal (4HNE) modifications, and malondialdehyde (MDA), resulting in lipid peroxidation, protein modification, and DNA oxidative damage 60

[24] In HER-2 positive tumor cells, increasing FOXO4 activity reduces tumor size

The resulting reaction originates from the interaction of a free radical with a non-radical species