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It also reduces the protein levels and mRNA expression of SIRT1, Nrf2, and HO-1 in the kidney [ 52 - 54 ]

[DOI] [Google Scholar] 59.Van Maldegem A.M., Bove J.V.M.G., Peterse E.F.P., Hogendoorn P.C.W., Gelderblom H

AlvarezPAlvaradoCPuertoMSchlumbergerAJimnezLDe la FuenteM.et al

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Human adipose mesenchymal stem cell-derived exosomes protect mice from DSS-induced inflammatory bowel disease by promoting intestinal-stem-cell and epithelial regeneration

Selective COX-2 inhibitors reduce gastrointestinal damage but may predispose patients to myocardial infarction and thrombosis by decreasing prostacyclin levels
