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Gastroenterology 116 :874884

In case of an emergency unblinding, the reason and time of unblinding will be documented in the study files

This is why heavy drinkers are at significantly higher risk even from smaller doses of acetaminophen

Cnossen MH, Stam EN, Cooiman LC, Simonsz HJ, Stroink H, Oranje AP, Halley DJ, de Goede-Bolder A, Niermeijer MF, de Muinck Keizer-Schrama SM

Diarrhea Diarrhea might seem contradictory given the constipation discussion, but GI motility disruption can manifest in either direction depending on the individual

At the lower doses used by most steroid users, discontinuation due to side effects is even less common