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Br J Cancer (2010) 103:8619.10.1038/sj.bjc.6605834 23 WeberGFLettGSHaubeinNC

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This suggests that HIF-1 may promote angiogenesis in response to hypoxia by up-regulating the expression of genes such as VEGF

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This approach has yielded promising results in the potential treatment of age-related decline in the elderly [151,152,153]
