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Efimova et al
[Epub ahead of print] 17
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Higher NAD enhances SIRT1 activity, promoting fat oxidation and mitochondrial remodeling via PGC-1 pathwaysmechanisms consistent with improved endurance and recovery potential (Cant et al., Cell Metabolism
doi: 10.1172/jci.insight.95997 30
However, as noted by Chen and colleagues 52 , this increase in FXR signaling could also be connected to depressive symptoms in FM
In fact, an open-label study showed that NAC reduced self-reported marijuana use without differences in the urine cannabis toxicology in young people [61]
