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An important factor to consider is that metabolism of in vitro cultured cells may not properly reflect cellular metabolism in vivo, given the high concentration of glucose in media
For instance, AD-related inflammatory responses could be attenuated after fecal transplantation in mouse models of AD, by modulating the release of inflammatory cytokines [84]

4-Hydroxynonenal (4-HNE), an outcome of the lipid peroxidation procedure (Jaganjac et al

Drazic G, Mihailovic N

The resulting N-methylhydantoin subsequently forms complexes with transition metal ions to generate a redox signal

Vitamin B-6 nutrition status and cigarette smoking