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Archives of Biochemistry and Biophysics , 171 (2), 490

Conversely, in patients with anorexia nervosa, even supra-physiologic GH doses (mean maximum daily dose: 1.4 mg/day) may not be sufficient to normalize IGF-I levels (61) indicating the important role of hepatic GH sensitivity in successful IGF-I generation

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Grogan PM, Gronseth GS