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doi: 10.1016/S0006-2952(03)00343-5

Through electrostatic and hydrophobic interactions with cardiolipin, SS31 prevents the oxidation of both cardiolipin and cytochrome C while disrupting their interaction (Szeto and Birk, 2014

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Further investigations revealed that mammalian lipoxygenase family member arachidonate 12-Lipoxygenase (ALOX12) is crucial for p53-dependent ferroptosis

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10.1002/jbmr.3117 85 SunX.DongS.LiX.YuK.SunF.LeeR