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Severe bouts of stress can trigger it

Within the schizophrenia group, oxidized glutathione (GSSG) demonstrated a significant moderate negative correlation with LDL cholesterol (r = 0.430, p = 0.032), indicating that higher LDL levels were associated with lower GSSG concentrations

aemia, certain gut surgeries, or dietary restrictions
In a recent and detailed study, Cheah et al

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PMID 33350388
