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Ivanova L, Uhlig S, Devreese M et al (2017) Biotransformation of the mycotoxin enniatin B1 in pigs: a comparative in vitro and in vivo approach

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Size, surface charge, and flexibility are important determinants for cellular internalization of NPs, with lipid-based NPs being more readily internalized than rigid silica or metal-based NPs ( The complexity of the physiological and pathophysiological barriers encountered during the systemic delivery of NPs to the brain complicates the development of successful NP-based therapeutics ( The review intends to give a broad and impartial presentation of the present status of nanoparticle-mediated drug delivery approaches for CNS disorders