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found that thymidine monophosphate (TMP) could promote the synthesis of TTP independent of TK2 in the cardiac mitochondria of rats in vitro , suggesting a potential therapeutic strategy for TK2 deficiency-related diseases ( SUCLG1 SUCLG1 gene encodes the -subunit of succinate COA ligases (SUCL, also known as succinyl CoA synthase)

For example, the GSK-3 degrader PT-65 ( 62 ), developed through click chemistry, exhibited a more prolonged effect on p-tau than its GSK-3 warhead (a GSK-3 inhibitor)

Restricted imidazole amount in the elution buffer due to the requirements in downstream applications or the target protein's sensitivity to imidazole

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We used a fully automated microplate reader to measure the levels of glutathione (GSH), superoxide dismutase (SOD), and malondialdehyde (MDA) in uterine tissues

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