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Dose Escalation Study of BET Inhibitor PLX2853 in Patients with Relapsed or Refractory Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

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Specifically, targeting DNA methylation in neurodegenerative contexts requires careful consideration of potential risks, such as side effects and long-term safety concerns

[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Toaldo I.M., Cruz F.A., da Silva E.L., Bordignon-Luiz M.T

A recent study demonstrated that autophagy activation can be triggered by IOP elevation and mechanical stretch in TM cells, and primary cilia are critical for IOP homeostasis and autophagy activation [134]

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