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Therefore, iron-induced animal models of kidney injury have been a valuable tool in studying the mechanisms of iron-induced kidney injury and testing the therapeutic effects of natural products or pharmaceutical drugs [122,123,124,125]

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A case report and review of the literature

Complementary clinical and meta-analytic data consistently demonstrate systemic redox imbalance, including lower glutathione reserves, altered GSH/GSSG ratios, increased lipid peroxidation, and dysregulated NRF2 signaling, linking oxidative status to immune activation and synaptic dysfunction (James et al., 2004
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